Rapidly destructive coxarthropathy with osteonecrosis and osteoporosis caused by Cushing's syndrome.

thy, characterized by severe joint destruction occurring within a few months, is ascribed to subchondral insufficiency fracture resulting from osteoporosis1 and ischemic hip disease.2 Corticosteroids can cause avascular osteonecrosis of the femoral head, osteoporosis, or both. Most cases of corticosteroid-induced osteonecrosis are caused by exogenous corticosteroid administered for the treatment of various diseases. A few cases of osteonecrosis caused by endogenous corticosteroid, such as in Cushing’s syndrome, have been reported previously. This article presents a case of rapidly destructive coxarthropathy with osteonecrosis and osteoporosis caused by Cushing’s syndrome.